![]() ![]() That means you need to restart the driver. If it has not been enabled properly, you will need to restart the “TabletDriverAgent” process. ![]() If it has been enabled, it will show as the screenshot below: If the driver interface shows “Device disconnected”, please check if the “TabletDriverAgent” process has been enabled properly in your Activity Monitor. And please confirm that the driver interface shows “Device connected” (as shown below). ![]() Make Sure the Driver Interface Shows "Device connected".Īfter the driver is properly installed, please open the driver and plug all cables correctly. You can simply open the software by clicking “Open”. If the software is not downloaded from App Store, the system will pop up a tip as below: The corresponding solution is as follows: If you are a new Huion user and have not installed any driver in your computer yet, please follow the steps below to install the driver:ġ) Go to Huion official website: and download the latest V14 driver.Ģ) Click the installation package >Drag the “HuionTablet” icon to “Applications” > Double click “HuionTablet” > Select “Open” to run the driver.ģ) After installation, the following problem may occur depending on the user's specific settings. To avoid the above hassles, we are providing some helpful solutions. The stylus can move the cursor but without pen pressure It shows “Device connected” in the driver interface but the stylus can not control the cursor on the screen ģ) Pen pressure sensitivity doesn’t work. – An “Unidentified developer” error message pops up and the tablet doesn’t respond at all.Ģ) Pen Cannot Move. Now, here are the most frequently seen issues with Mac Mojave:ġ) Popup Error. Please check the following link and learn how to uninstall V13 or V14 driver properly: How to Uninstall the HUION MAC Driver V13 or V14 Properly Recently updated your Mac to the latest OS Mojave or Catalina and can’t get your Huion device to work with it? Don’t worry! We’ll walk you through to get your device working again!īefore we start, first you may need to make sure that you’ve uninstalled all previous Huion drivers correctly. ![]()
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![]() It is also mentioned in this same secretly recorded conversation that, at that time, John had killed fewer than 10 people, while DeMeo had killed at least 38. The FBI had been surveilling the warehouse and some of the men unloading vehicles there and had shortly thereafter obtained a search warrant.ġ8-year old college student, mistaken for a Cuban hitman parked outside his home. said after the sentencing, adding that DeMeo “engaged in wholesale murder.The son and brother of Joseph Viggiano, both were lured to a meeting and shot to death by Roy DeMeo after investigating the disappearance of Joseph. “The Roy DeMeo crew is the most violent crew ever prosecuted in federal court, as far as my knowledge,” Assistant U.S. He was taken off the board in December 1985 in front of Sparks Steak House in Midtown Manhattan, paving the way for the Teflon Don, John Gotti. Mob boss Castellano wouldn’t last much longer. They left his corpse in the trunk of his 1983 Cadillac and parked it at a marina.Īfter members of the yacht club complained enough, cops came and found Demeo. Roy Demeo barely had his coat off when Gaggi and other crew members pumped scores of bullets into his body, seven of them into his head.īut his minions didn’t make Demeo - one of the most psychopathic killers in mob history - disappear. ![]() There, he met with his mentor Nino Gaggi, now a Gambino capo. The 42-year-old Demeo was lured to a garage in Brooklyn that his gang had used. The beginning of the end came when an 18-year-old college student working as a vacuum-cleaner salesman was mistaken for a Cuban hitman by the increasingly paranoid Demeo who proceeded to shoot the kid. HANDOUT/ NYPD Photo by HANDOUT / NYPDīut the clock was ticking on Roy Demeo and his crew. Gambino boss Paul Castellano had had enough of Demeo. “Roy instructed me and Henry (Borelli), believe it or not, to go and buy some pizza.” “Roy said, ‘We have to cut them up,’” Vito Arena later testified. Turncoat Dominick Montiglio testified in court: “Somebody would wrap a towel around to stop the blood and somebody would stab him in the heart to stop the blood from pumping.” When the doomed arrived at the upstairs apartment - called the Horror Hotel - they were greeted by crew member Joseph “Dracula” Guglielmo. Years later, a heartbroken Demeo would have to park a bullet in Rosenberg’s skull at the behest of mob bosses. The first street hood to sign on was 16-year-old Chris Rosenberg, a neighbourhood dope dealer. He joined Gaggi in a loansharking racket and began building his own crew of car thieves. In 1966, he was recruited by Gambino talent spotter Anthony “Nino” Gaggi and the young butcher signed on. ![]() Gambino captain Anthony “Nino” Gaggi was a mentor. His older brother was killed in the Korean War. ![]() He was born in Brooklyn in 1940 to hard-working Italian immigrant parents. The mobster would eventually become too violent to live. The Gambino crime family soldier oversaw a bloodthirsty crew of killers that was eyed in as many as 200 gangland murders from the 1970s to the early 1980s.ĭemeo was a one-time butcher’s apprentice who found his true calling in the ranks of New York City’s underworld. This advertisement has not loaded yet, but your article continues below. ![]() ![]() ![]() In the sheet that pops up, tap Copy to 1Password. Tap “Import into new 1Password” if you’re asked to import your data. How do I transfer my iphone password to 1Password? You can import Bookmarks, History, Passwords, or any combination thereof by checking the appropriate boxes. Open Safari, go to File > Import From, and choose Chrome or Firefox. How do I import a password from Safari to CSV? You can also open the Keychain file in the Finder or, if you use Time Machine to back up your files, you can restore the file with Time Machine. ![]() In the Keychain Access app on your Mac, choose File > Add Keychain. ![]() Recover items stored in a deleted keychain How do I recover old keychain files on Mac? in macOS, use Applications > Utilities > Keychain Utility and click the iCloud keychain in the Keychains list or use Safari via Safari > Preferences > Passwords. How do I recover passwords from Safari? On an existing device with iCloud Keychain, you can retrieve Safari and app passwords in iOS via Settings > Passwords & Accounts > Website & App Passwords. Open the Apple Menu in the top left corner of your screen.Īlso know How do I export keychain passwords to LastPass?Ĭlick the LastPass icon in your browser’s toolbar, then click More options. How do I save my keychain passwords to iCloud? Next, See all Safari and app passwords saved in your iCloud > Click on More button at bottom > see option for Export passwords > Save in to CSV file. Go to apple logo from top mac menu > System Preferences > Passwords. If you were to restore a system from its Time Machine backup, your Safari website passwords will be restored along with everything else.Īccordingly, How do I export apple passwords to CSV? Time Machine will back up your Keychain and no additional steps are necessary for it to do that. Safari stores its passwords in the keychain. Thereof, Does Time Machine backup Safari passwords? Select a location to save your keychain items, click the File Format pop-up menu, then choose a file type. In the Keychain Access app on your Mac, select the items you want to export in the Keychain Access window. ![]() ![]() ![]() In addition, he also offered consulting services and media training for aspiring esports pros and personalities. Since retiring as a competitor, Robinson has moved into a second career as a broadcaster, covering esports events, hosting, and streaming daily to almost 115,000 followers on his own Twitch channel. Seattle, Washington Died: J(aged 33) Race: Protoss Alternate IDs: EG.iNcontroL, RedeemeR, WINDRAMMER Approx. Robinson is one of the best known personalities in the history of StarCraft spanning both Brood War and StarCraft 2, most famous for the sense of humor and delivery that helped him improve any broadcast he was a part of. Robinson was a competitive StarCraft player and part of the first Evil Geniuses team to compete in the game. StarCraft commentator, analyst, streamer and ex-pro Geoff 'iNcontroL' Robinson has died at the age of 33. Let's live today in his example of love and laughter." ![]() BARRISTAN is safe in the care of friends, and family will share words of remembrance when they are ready. ![]() "Geoff is deeply loved across many communities and we're all working to make sure his affairs are in order as he'd want. To honor Geoff or offer comfort to his family, we suggest donations to, which he loved. "We ask privacy as his family works to understand what happened and make arrangements. "With immense grief, we announce Geoff's unexpected passing due to sudden illness Saturday," read the statement posted on his Twitter account. Bacteria In Control Of Life, Death, & Evolution (Paperback) - Common on. The 33-year-old Twitch streamer and esports host's social media channels were updated over the weekend with news of his passing. Credit: The Advertiser/Supplied Lily Thai was in ‘excruciating pain’ and engaged the state’s voluntary assisted dying laws, which were introduced in January.Geoff Robinson has died. Lily Thai died on Wednesday afternoon, her funeral notice confirmed. Today, official social media accounts of Geoff 'iNcontroL' Robinson revealed the gaming personality, host, commentator, and former StarCraft 2 player passed away yesterday at the age of 33. ![]() “It’s gotten to the place that I’ve lost control of everything else in my life, and I’ve been reliant on my dad as a caregiver to do everything for me, even the most intimate things,” she told the local newspaper. She discovered her organs were failing due to an autoimmune disease known as Autoimmune autonomic ganglionopathy. Was drawn into seeing Incontrol with a cool poster/cover, a very intriguing and creative premise (one of the most innovative for any film seen recently). What we have for confirmation is a series of posts from Robinson’s official social media accounts stating that Robinson has passed away suddenly from a sudden illness. At this time, no cause of death has been revealed. Voluntary assisted dying was legalised in South Australia in January, six years after Thai was diagnosed with Ehlers Danlos Syndrome (EDS), which causes the sufferers joints to become loos and their skin fragile - putting them at risk of severe injury.Ī year later, she lost her ability to walk, use her bowels, eat and drink without becoming sick. The gaming personality has passed away suddenly at the age of 33-years old on this past Saturday night. Laughing so hard your face starts to hurt. Every time the man got on the mic during a cast you knew it was going to be good. Treasured friend to many,” the family said in the notice. Hopping over to r/StarCraft there is a ton of great clips of Geoff being Geoff. Watch the latest news and stream for free on 7plus > ![]() ![]() ![]() We also learned it the hard way after our YouTube account was compromised and all videos were deleted. Security and privacy are often neglected while choosing streaming software. On Mac, due to Apple’s restriction, it’s tricky to use some advanced features of OBS like sharing internal audio. In our experience of using OBS for almost a year, we found it to be a little complicated to set up and works best on a powerful PC. Since it’s a web-based tool, it’s more suitable for streamers who are on the move. Verdict: StreamYard is much easy to set up and use. You will see the stream key in your live dashboard.From your YouTube Studio, select the option to GO LIVE.You can read more about the OBS set-up guide, however, here’s a basic idea to get started with OBS. No support for smartphones or Chromebooks as of now. OBS, on the other, is also available on Windows, Mac, and Linux. ![]() Sign up for StreamYard if you haven’t already.Launch Chrome or another supported browser.Your guests can also join on their phones without any need for registration. In fact, you can even use StreamYard on your Android and iOS (Safari only) right from your browser, without having to download any app. This means it works on any entry-level computer which has a web browser, be it your Windows, Mac, Linux, or even low power Chromebooks. The second thing to consider before picking up streaming software is the setup and installation process. We started using the free plan of StreamYard but after a few live sessions, we decided to go pro as well. Verdict: If you plan to use StreamYard, eventually, you will have to spend money to get the best out of it. However, you will have to spend some time configuring these options and learning how the software works. This means you get all the premium features like 1080p stream, multiple cameras, on-screen participants at no extra cost. The $49 plan offers everything you get in the $25 plan, plus 1080p and multiple cameras. You can also have 10 on-screen participants in this plan, while the free version allows only 6. ![]() We are using the $25 plan which removes the StreamYard watermark and gives you the option to have a custom logo, overlays, and background. There are two paid plans ⏤ $25 per month and $49 per month. Most streamers (including us) didn’t like this watermark and moved to the paid plans. StreamYard is free to join, however in the free version, you get a StreamYard watermark and 20 hours per month streaming limit. One of the most important things to consider before picking up streaming software is the price. Detailed StreamYard vs OBS Comparision 1. Which one you use would depend on your specific needs. They also offer the flexibility to utilize custom layouts, screen share, and third-party tool integrations. StreamYard and OBS are two popular third-party apps that let you live stream on YouTube. ![]() ![]() ![]() But it certainly has not acquired the information to become a land animal. It is actually fairly restricted in its habitat, perhaps due to a loss of genetic variability within its created kind. It is breathing using the same anatomical equipment God equipped aquatic creatures with on the fifth day of Creation. The blenny is not making any evolutionary progress toward becoming a terrestrial creature. Ord admits, “At the end of the day, they are still fish, and fish are more suited to life in water, not on land.” 5 Instead, the “evolutionary” changes evidently restricted this fish to a very limited survivable environment. Ord believes that these fish “provide a unique opportunity to study the various steps-essentially ‘evolutionary snapshots’-in the invasion of land by marine fish as well as the selection pressures faced at different stages during a major ecological transition.” 3 But she says the blennies’ territorial possibilities are quite “constrained by their evolutionary history.” 4īy evolutionary standards, the blenny’s move toward land should have provided a survival advantage if those adaptations were to be preserved. In fact, blennies must restrict almost all their activities “to a brief period at mid-tide.” Then the water is high enough to keep them moist but low enough to keep them from being swept out to sea.ĭr. Male blennies are territorial and try to attract females to their rock holes. To reach higher ground in a hurry, they can also twist their bodies and flick their tails to leap many times their own body length.”īlennies do not voluntarily return to the water, avoiding submersion in spite of the incoming waves. They move quickly over complex rocky surfaces using a unique tail-twisting behaviour combined with expanded pectoral and tail fins that let them cling to almost any firm surface. ![]() Ord adds, “I can tell you they are very hard to catch and are extremely agile on land. Blennies also do not have limbs but manage to squirm around on the wet rocks. The fish of course does not have lungs and therefore must “stay moist to enable it to breathe through its gills and skin,” Ord explains. Remarkably, representatives of all these types can be found on or around Guam, making it a unique evolutionary laboratory. Within the blenny family, however, are species that are either highly terrestrial, amphibious or entirely aquatic. We know that our ancient ancestors evolved originally from lobe-finned fish but, today, all such fish are fully aquatic. “The Pacific leaping blenny offers a unique opportunity to discover in a living animal how a water-land transition has taken place,” says Dr Ord. Terry Ord spent some time observing the blenny’s behavior hoping to discover some evolutionary secrets of our aquatic past. Because the blenny has “made a highly successful transition to land,” 2 Dr. Many fish have an amphibious streak in their behavior, but the Pacific leaping blenny is “one of the rare living examples of a fish that spends the vast majority of its time on land.” 1 The blenny is native to intertidal zones on the rocky coasts of Micronesia. Earth Times: “ The Jumping Fish with a Tale of the Earliest Land Creatures”. ![]() ![]() The salient features of the chapter include structure of MongoDB database, MongoDB database design considerations, and data modelling in MongoDB. The final Chapter 3 is devoted to exploring the concepts of MongoDB which is the most popular NoSQL database management system. This book is aimed at web developers who are familiar with frontend technologies. The highlights of this chapter are attributed to handling dynamic routes, understanding of different intricacies associated with middlewares, and child routing. Learning Single-page Web Application Development Fernando Monteiro. Chapter 2 is devoted to the understanding of core concepts of Express.js. Chapter 1 explores the core concepts of Node.js starting with setting up of Node.js environment and exploring Node Package Manager (NPM). Vol -I of book on MEAN Stack Web Development Explained to Novice Learners – Vol I (Covers Node.js, Express.js and MongoDB) is divided into three chapters on Node.js, Express.js and MongoDB. Each concept is demonstrated with fistful of programs which enable the reader in gaining in-depth knowledge in each of these areas. The book aims at providing conceptual understanding of main concepts which enable the learner in applying the concepts to the real life problems required towards live application development. She bears a varied and rich experience in the field of computer programming. ![]() ![]() She has authors 35 plus books in various cutting edge technologies in computers. She has over 50 research papers in various international and national journals to her credit. Her academic credentials are distinctly different. Naik is currently working as a Professor an Head of Department of Computer Studies at CSIBER, Kolhapur. ![]() ![]() ![]() Many are already recommending fourth doses for those at highest risk of severe disease, given recent studies highlighting the additional benefit provided. Public-health authorities around the world are considering short- and medium-term strategies for the timing and rollout of booster shots. Vaccines, therapeutics, and testsĪlthough advances in detecting and treating COVID-19 lead the news less frequently than they did a year ago, important developments continue to emerge. The vaccines now in wide distribution still limit the incidence of severe disease. For the moment, however, scientists view these variants as simply more transmissible than Omicron. 6 Yunlong Cao et al., “BA.2.12.1, BA.4 and BA.5 escape antibodies elicited by Omicron infection,” To be sure, some tentative evidence that BA.4 and BA.5 can evade immunity is emerging. But so far, they haven’t fundamentally changed the dynamics of the pandemic, because there hasn’t been a step change decline in immunity, as seen during the winter, when Omicron first emerged. Subvariants of Omicron, especially BA.5, have challenged the world with ever more transmissible versions of the virus. ![]() Delta-cron (Omicron’s twin) and Milder-cron scenarios we described in our March 2022 update remain a reasonable summary of the range of possibilities for the impact of future variants. ![]() Second, a new, immunity-evading variant could upend this relatively optimistic story at any time. 5 “Coronavirus in the US: Latest map and case count,” New York Times, J“Past seasons estimated influenza disease burden,” US Centers for Disease Control and Prevention, accessed July 24, 2022. While many people in the United States are growing comfortable living alongside COVID-19, the average number of daily deaths still runs at two to four times the long-term average for influenza, and it’s higher on a seasonally adjusted basis. First, the term “relatively favorable” needs qualification. The winter of 2022–23 may see a more substantial uptick in the Northern Hemisphere, but this is unlikely to be as severe as the December 2021–February 2022 wave. Looking ahead, the outlook for most regions, including Europe and North America, remains relatively favorable for the coming months, with levels of severe disease at or below recent levels. 4 Paul Mozur and Alexandra Stevenson, “In China, concerns grow over the economic impact of ‘zero Covid,” New York Times, Ji Siqi, “China coronavirus: Shanghai restrictions caused ‘more severe economic hit’ than previous lockdowns, China Macro Economy, June 1, 2002. ![]() In the meantime, the current approach appears to have had substantial and mostly negative effects on both the Chinese and the global economies. Nonetheless, the relatively low levels of immunity among the population, including the elderly, make the endgame for this approach less clear than it is for countries that have shifted away from a zero-COVID-19 strategy. That approach has kept the number of deaths caused by COVID-19 low. 3 Rhiannon Williams, “China is sticking to its zero-covid plan, and how Ukraine is rebuilding its destroyed cities,” MIT Technology Review, May 9, 2022. 2 “Estimating excess mortality due to the COVID-19 pandemic: A systematic analysis of COVID-19-related mortality, 2020–21,” Lancet, March 10, 2022.Īs of mid-July 2022, mainland China is the only large country pursuing a zero-COVID-19 strategy. The experience of these countries, with total excess mortality from the pandemic far lower than it is in other parts of the world and only a limited need for ongoing restrictions, can make a case that their response to the COVID-19 pandemic has been among the most effective in the world. They have seen continued success, recording higher case counts but few deaths. Countries such as Australia and New Zealand have decreased their previously strong focus on controlling viral spread and are now transitioning to strategies for managing endemic disease. 1 “Coronavirus pandemic (COVID-19),” Our World in Data, accessed July 24, 2022. While the BA.5 subvariant has produced a rise in the number of cases in many places, the burden of severe disease remains low in Europe and is only moderately higher in the United States, thanks to the lower average severity of Omicron subvariants and high levels of partial immunity. The past few months have seen many parts of the world, including Europe and North America, continue their journey toward endemic COVID-19. ![]() ![]() ![]() The main downside was that the part as printed was virtually impossible to remove from its support material. The resin still yielded a part with reasonably crisp lines, although as expected the layers were quite visible. Indeed, migrating the design to the draft resin reduced the print time down to under 4 hours, which was a welcome relief for a quick test print. This was not going to cut it for a quick test print! Fortunately, Formlabs had also sent me a sample of their “draft resin”, which advertises itself as a way to rough out quick, low-resolution prints. The design I had chosen was quite large, requiring over 18 hours to print in clear resin. So, I went and downloaded a couple of popular-looking prints from the Internet and loaded them into the latest version of the Preform software. The Form 3 build platform is a little larger than the Form 1, but it turns out there are a number of good reasons for the extra size, which we’ll get into later.īefore taking the whole machine apart, I decided I’d give it at least one test print. My first impression of the Form 3 was, “wow, this is a big machine”.Ībove is a Form 3 next to a Form 1 for size comparison. I always learn an immense amount while taking apart their machines, and it’s also been very satisfying to watch their engineering team grow and mature over the years. With the recent release of the Form 3, I was asked by Formlabs if I wanted to do another teardown, and of course I jumped on the opportunity. It’s been my privilege to do teardowns on both the Formlabs Form 1 and Form 2. ![]() ![]() ![]() 10 9 The growth phenotype is thought to be due to the observed upregulation of the early growth response factor 1 gene ( EGR-1) and ectopic expression of the high mobility transcription factor coding genes HMGA2 has been reported in a few cases. 9 PIG-A mutant cells have been demonstrated to be less sensitive to T lymphocytes and, along with leukemic cells with the same mutation, possess increased resistance to natural killer cells. ![]() Loss of ULBP1 may prevent their destruction by NKG2D lymphocytes allowing for immune-escape from ULBP-NKG2D engagement in the bone marrow. 8 The UL16 binding protein 1 (ULBP1), a stress-induced ligand for the NKG2D receptor, is a GPI-linked glycoprotein thought to be lost on PNH stem cells. Two mutually cooperative hypotheses exist to explain the clonal expansion of PNH cells one involves immune selection-mediated expansion and the second predicts that dominant PNH clones acquire a growth advantage. The process behind the clonal expansion of the PIG-A mutated stem cells in PNH patients is not fully understood. 7 This implies that the presence of the PIG-A mutation alone is not sufficient to allow the PNH clone to dominate. 1 Studies have shown the presence of a small number of GPI anchor deficient cells in the blood of healthy controls as well as in patients with PNH. 6 GPI, a glycolipid moiety, anchors numerous proteins to the cell surface, with more than 12 GPI-anchored proteins (GPI-APs) located on hemopoietic cells. The PIG-A gene codes for an enzyme involved in the formation of the N-acetylglucosaminyl phosphatidylinositol biosynthetic protein which is necessary for the first step in the biosynthesis of glycosylphosphatidyinositol (GPI) anchors. 5 PNH is caused by an acquired inactivating mutation of the PIG-A gene located on the X chromosome. The incidence of PNH is estimated at 0.1–0.2/100,000 persons per year. Paroxysmal nocturnal hemoglobinuria pathophysiology 4 3 The review herein will discuss changes to the hemostatic system in PNH, and highlight areas that require future research in the prothrombotic processes involved in PNH. 3 Multiple proposed mechanisms behind the increased incidence of thrombosis include a prothrombotic state in conjunction with platelet abnormalities and impaired fibrinolysis. 2 Despite such a large role in the burden of the disease, the mechanism behind the development of thrombosis is poorly understood, highlighting the importance of thrombosis management in PNH patients and elucidating more information regarding the nature of the thrombotic event. 1 Thromboembolic events are the most common cause of morbidity and mortality in PNH and account for 40–67% of deaths 40% of patients having suffered an event before diagnosis and 29–44% of patients suffering at least one event throughout the course of their disease. It is caused by an acquired mutation in the X-linked phosphatidylinositol glycan class A gene ( PIG-A), causing stem cell progeny (mature blood cells) to lack complement regulatory proteins and exposing them to complement attack. Paroxysmal nocturnal hemoglobinuria (PNH) is a rare hematologic disorder of multipotent hematopoietic stem cells. Further studies, including novel in vivo and in vitro thrombosis models, are required in order to define the role of the individual mechanisms contributing to thrombosis, impaired fibrinolysis and clarify other complement-driven prothrombotic mechanisms in paroxysmal nocturnal hemoglobinuria. While many factors may affect thrombosis in paroxysmal nocturnal hemoglobinuria, the relative contribution of each mechanism that has been implicated is difficult to quantify. Impaired fibrinolysis has also been observed and may be caused by several mechanisms involving interactions between complement activation, coagulation and fibrinolysis. ![]() Platelet and endothelial microparticles as well as oxidative stress may play a role. Paroxysmal nocturnal hemoglobinuria leads to a complex and multifaceted prothrombotic state due to the pathological effects of platelet activation, intravascular hemolysis and neutrophil/monocyte activation. This review article discusses the different factors that contribute to the increased risk of thrombosis in paroxysmal nocturnal hemoglobinuria. The increased incidence of thrombosis in paroxysmal nocturnal hemoglobinuria is still poorly understood, but unlike many other thrombotic disorders, predominantly involves complement-mediated mechanisms. Paroxysmal nocturnal hemoglobinuria is a rare acquired hematologic disorder, the most serious complication of which is thrombosis. ![]() |
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